Endocrine Abstracts

Iron deficiency anemia (IDA) is the most pervasive of all nutritional deficiencies and is considered very serious during pregnancy, with deleterious consequences for both the mother and her developing fetus. The female albino rats of Wistar strain were fed on iron deficient diets (30, 15, 7 and 2 mgFe/kg of diet) and control diets (50 mgFe/kg of diet). Prior to one month of mating the females were anaesthetised by ether and the tail blood was collected for the evaluation of bl...

ObjectiveThe aim of the study was to evaluate the peripartum changes in the level of anterior pituitary hormones, due to iron deficiency anaemia and also to evaluate whether severe iron deficiency anaemia leads to postpartum pituitary changes.MethodThe female albino rats of Wister strain were fed on iron deficient diets (30, 15, 7.2 mgFe/kg of diet) and control diets (50 mgFe/kg of diet). Prior to one month o...

Human obesity is characterized by abnormalities in sympathetic cardiovascular control. We present two cases to demonstrate the relationship between weight, BP and catecholamines (UC).Case 1: A 39 year-old man reported symptoms of flushing and palpitations. His BMI was 50 kg/m2, consistent BP of 240/140 mmHg, with normal renal, thyroid function and normal fasting glucose. Urinary noradrenaline (UNA820 nmol/24 hrs) and dopamine (UDA-4500 nmol/24...

Adrenal tumors are not uncommon in endocrine practice. We collected retrospective data from our clinical records of our patients with adrenal tumors from 2021 January to 2023 January. There were a total 20 patients; males 10 (50%) and females 10 (50%). Mean age was 47.4±10.65 years and average BMI was 26.57±4.94. Hypertension was seen in 13 patients (65%) and diabetes in 9 patients (45%). Nonfunctioning adrenal adenomas (NFAAs) were seen in 12 patients (60%) and function...

Pituitary tumors are infrequently seen in an endocrine practice. We collected retrospective data from our clinical records of our patients with pituitary tumors from January 2018 to December 2023. There were a total 31 patients; males 9 (29.03%) and females 22 (70.97%). Mean age was 38.54±12.37 years and average BMI was 26.10±3.91. Headache and visual problem was the most common symptom in 13 (41.9%) patients each followed by menstrual irregularity in 8 (25.80%) patients...

Background: CGM based monitoring can help in development of personalized digital therapeutics programs based on the understanding of the effect of diet, physical activity and medications on everyday blood glucose excursions. The variation in intra-individual glycemic response to the same food has been reported in many studies. Thus, understanding of personalized glycemic response (PGR) of each individual becomes important for effective diabetes management.<p class="abstext...

81-year-old ex-smoker presented to emergency with transient facial droop, slurring of speech and generalized weakness. He had a background of ischemic heart disease, hypertension, and previous bladder cancer (treated 5 years ago). Examination revealed clinical signs of hypocalcaemia with no cushingoid features. Bloods revealed refractory severe hypokalemia, severe hypocalcaemia with normal phosphate, and metabolic alkalosis requiring High dependency Unit.<p class="abstext"...

A 37 year-old gentleman presented following an episode of dizziness while at work operating a fork-lift truck. There was no collapse or associated symptoms. He had been diagnosed with autoimmune hypothyroidism two months previously; commenced levothyroxine, currently at a dose of 75 micrograms daily; and lost ten kilograms in weight. On examination there were no signs of hypoadrenalism aside from a significant postural drop in blood pressure (lying 1...

A 37 year-old gentleman presented following an episode of dizziness while at work operating a fork-lift truck. There was no collapse or associated symptoms. He had been diagnosed with autoimmune hypothyroidism two months previously; commenced levothyroxine, currently at a dose of 75 micrograms daily; and lost ten kilograms in weight. On examination there were no signs of hypoadrenalism aside from a significant postural drop in blood pressure (lying 1...

The first case is a 19-year-old male who presented to his GP with lumbar pain, scrotal bruising, and weight loss. Abdominal CT showed a left 6.4 cm x 12 cm suprarenal mass; the right adrenal gland was atrophic. Plasma metanephrines and MIBG were normal. Urinary steroid profile (USP) showed raised 11-deoxycortisol, consistent with adrenocortical carcinoma (ACC). He underwent a left nephrectomy and adrenalectomy. Histology confirmed ACC. The lesion was encapsulated with negative...